In answer to my experience with autophagy, my skin has been firming up as I lose. Many of my age spots are gone as are most of my skin tags (which, by the way, are becoming recognized as an indicator of Diabetes). I had dark patches of skin in folds, under my breast and in my groin area (can't remember the name for this condition, but it's slso an indicator for Diabetes) and it's mostly gone as well. But, the main reason I am doing extended fasting is to heal my insulin resistance.